Design Approach
When building worlds, there's a risk of becoming overwhelmed by the sheer number of decisions to be made. Remember that you don't need to make every decision for every aspect of your world all at once. Focus first on the elements you need for your story and the game, then add as much of the rest as you'd like. You'll also want to allow room for input from your players—gaming sessions are more memorable and engaging when the storytelling experience is shared between everyone at the table (Narrative Collaboration has more information on players contributing to the narrative).
Before you decide anything else, however, you should establish your concept and your goals. Do you envision a bustling port of call in Near Space? A star system where magic comes from quarreling regional deities who each control a separate warring planetoid? A low-tech moon unknowingly isolated from the rest of a high-tech system full of starships? Are you designing a whole region of space for a multi-year campaign, or a single settlement on a world for a fast-paced one-shot adventure? Having an idea in mind will help steer your choices as you build your worlds, and knowing your goals will help you focus on building what you need.